Galangin

Name: Galangin
Synonym: 4H-1-Benzopyran-4-one, 3, 5, 7-trihydroxy-2-phenyl-
CAS: 548-83-4
Molecular Formula: C15H10O5
Molecular Weight: 270.23
Botanical Source: Alpinia officinarum Hance Root
Major Functions:
Several recent studies with this flavonoid suggest that it may have a potent anti-cancer effect, specifically through inhibition of the detoxification enzyme CYP1A1 and modulation of the aryl hydrocarbon receptor The implication with this type of research is that this flavonoid exerts a protective effect against the carcinogenic potential of overcooked, char-grilled foods. Galangin has also been shown to be a potent preserver of the endogenous free radical scavenger glutathione, thereby playing another anti-carcinogenic role. Recent research has also uncovered several mechanisms by which this particular flavonoid exerts a positive effect in the prevention of heart disease. Galangin has a proven anti-oxidative effect on endothelial tissues and acts to help preserve other protective antioxidants such as vitamin E, vitamin C and other flavonoids, in this function it also serves to prevent lipid peroxidation11. Galangin also exerts a strong inhibitory effect on the cyclo-oxygenase family of enzymes, this provides a strong cardioprotective effect by inhibiting the aggregation of platelets, as well as providing a consistent systemic anti-inflammatory effect.